Tuesday, April 08, 2008

Lung Pathology: Molecular markers for adeno, scc, lung adeno vs. papillary thyroid

Lung Adenocarcinoma

TTF-1(+)
m-ive (-)
CYTO20(-)
CK7 (+)

Squamous Carcinoma

Two characteristics:
1) Intercellular bridges
2) Irregular chromatin, ugly nuclei
CK7(-)

Lung Adenocarcinoma vs. Papillary Carcinoma of Thyroid

Both TTF-1(+)
Calcitonin(-) in lung adeno
thyroglobulin (-) in lung adeno
Prominent Nucleoi in Adenocarcinoma